Airways Disease Biology Research Group

The Airways Disease Biology Research Group is dedicated to advancing our understanding of respiratory diseases through cutting-edge research in respiratory physiology, biomarkers, and molecular mechanisms. Led by Dr. Stephen Milne, a specialist in respiratory and sleep medicine, the group explores the biological underpinnings of diseases such as chronic obstructive pulmonary disease (COPD) and investigates novel diagnostic and therapeutic approaches.

Research Themes

  • Respiratory Physiology: Investigating lung function and mechanisms of airway disease.
  • Chronic Obstructive Pulmonary Disease (COPD): Understanding disease progression, phenotypes, and personalized treatment strategies.
  • Biomarkers: Discovering and validating biomarkers to improve diagnosis, monitoring, and treatment efficacy in respiratory diseases.

Key Research Areas

  1. COPD:
    • Identification of biomarkers to predict exacerbations and disease progression.
    • Understanding the impact of systemic and airway epigenetic disruptions on health outcomes.
    • Investigating the effects of inhaled corticosteroids on the airway microbiome.
  2. Post-COVID-19 Lung Disease:
    • Examining the cellular landscape alterations in airway mucosa in long COVID.
    • Systematic reviews and meta-analyses of pulmonary imaging and post-COVID-19 dyspnoea.
  3. Advanced Diagnostic Techniques:
    • Development of novel physiological measurements and models for respiratory disease assessment.
    • Integration of omics technologies for biomarker discovery.
Group Members
  • Stephen Milne
  • Robert Robles

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