The Kidney Injury Group investigates mechanisms of cellular injury driven by the protein thrombospondin-1 and its receptor CD47. The laboratory focuses specifically on acute and chronic kidney disease, the sequelae of diseased organ cross-talk, and the translational potential of its research.
Recent Achievements
- Publication: https://www.science.org/doi/10.1126/scitranslmed.add2387 (associated patent PCT/AU2021/051241 for MODULATING INSULIN EXPRESSION AND PRODUCTION BY TARGETING CD47)
- Transplantation Society of ANZ awards to Natasha Rogers, Atharva Kale, Harry Robertson, Ahmer Hameed: https://tsanz.com.au/awardsandfellowships/tsanz-2023-award-winners.htm
- Australia’s first machine perfusion transplant kidney: https://www.9news.com.au/national/western-sydney-father-becomes-first-australian-to-receive-revived-donor-kidney-health-news/f3a03a7b-2039-4210-a413-fb17d48bfefd
Recent publications

A metabolic role for CD47 in pancreatic β cell insulin secretion and islet transplant outcomes. Sci Transl Med. 2023;15(717):eadd2387.
October 2023

Tolerogenic dendritic cells protect against acute kidney injury. Kidney Int. 2023 Sep;104(3):492-507.
September 2023

Disease-modifying interactions between chronic kidney disease and osteoarthritis: a Disease-modifying interactions between chronic kidney disease and osteoarthritis: a new comorbid mouse model. RMD Open. 2023 Aug;9(3):e003109.
August 2023

The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-κB activation in acute kidney injury. Kidney Int. 2023 Jun;103(6):1105-1119.
June 2023

Transcriptomic Analysis Identifies A Tolerogenic Dendritic Cell Signature. Front Immunol. 2021 Oct 20:12:733231.
October 2021
Group Members
NAME | ROLE |
Dr Sohel Julovi | Senior Scientist |
Dr Jennifer Li | Consultant Nephrologist, Postdoctoral Fellow |
Dr Cuicui Xu | Research Assistant |
Ms Sally Coulter | Research Assistant |
Dr Katie Trinh | Consultant Nephrologist, PhD student |
Dr Jana Pittman | Obstetrics & Gynaecology registrar, PhD student |
Ms Atharva Kale | PhD student |
Mr Harry Robertson | PhD student |
Ms Preeti Sharma | PhD student |
Mr Aadhar Moudgil | Masters student |
Dr Harsham Choksi | Surgical intern, Masters student |
Ms Catherine Wilson | MD PhD student |