Professor Fernandez-Peñas and his team pioneer non-invasive methods for early skin cancer diagnosis, aiming to replace biopsies. They explore non-invasive technologies to analyse skin surface proteins, potentially revolutionizing the diagnosis of various skin conditions, including melanoma and non-melanoma skin cancers. In NSW, their team leads a project deploying a network of 3D photography systems across Australia, aiming to enhance melanoma diagnosis through Artificial Intelligence. Simultaneously, they collaborate with researcher from the University of Sydney and the Nano Institute, utilizing quantum technology to develop new molecules for skin cancer treatment and improved/enhanced sunscreens, as well as addressing a challenge in drug development posed by the limitations of conventional computers in predicting quantum chemical dynamics
Recent Achievements
- Prof Pablo Fernandez-Penas together with other researchers from the University of Sydney received $1.5 million in grant funding through Wellcome Leap Quantum for Bio program to accelerate applications of quantum computing in skin and demonstrate quantum-enabled solutions to address skin health challenges..
- Dr Rachel TEH successfully completed her PhD: Dr Teh joined the Melanoma and Skin Cancer Group in 2019 as a PhD student to work on proteomic studies of early melanoma lesions. During her studies, she processed hundreds of samples of early melanoma lesions using proteomic technology and identified protein biomarkers that could assist with the early diagnosis of the lesions.
- Dr Azimi was invited to deliver a Keynote Speech at the High School Cancer Symposium held by Young Australian Cancer Initiative at the Westmead Institute for Medical Research on in Nov 2023. He delivered a talk on melanoma biology and how healthy melanocytes may turn nasty and become cancerous.
Recent publications

Non-invasive diagnosis of early cutaneous squamous cell carcinoma. Exp Dermatol
November 2023

Proteomic profiling of cutaneous melanoma explains the aggressiveness of distant organ metastasis. Exp Dermatol
July 2023

ACEMID cohort study: protocol of a prospective cohort study using 3D total body photography for melanoma imaging and diagnosis
September 2023

Data Independent Acquisition Proteomic Analysis Can Discriminate between Actinic Keratosis, Bowen's Disease, and Cutaneous Squamous Cell Carcinoma
January 2020

Investigating proteome changes between primary and metastatic cutaneous squamous cell carcinoma using SWATH mass spectrometry
August 2020
Group Members
![]() Research Staff Dr Ali Azimi Dr Rachel Teh Dr Gulietta Pupo Lauren Faul Grace Kwaan
Masters Students Petrina Chand Dr Raquel Ruiz Araujo Honours Students Manail Touqeer Websites Western Sydney Local Health District Twitter/X @CTSR_USyd Centre for Translational Skin Research @PabloFP_Syd Prof. Pablo Fernández-Peñas
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