Jacob George

Professor

Centre Director

MBBS/FRACP/PhD/FAASLD

jacob.george@sydney.edu.au

The Storr Liver Centre

Ageing liver and metabolic fatty liver diseases

Jacob George

Biography

Professor Jacob George is a clinician investigator and Robert W. Storr Chair of Hepatic Medicine, University of Sydney (2007-) and Head, Department of Gastroenterology and Hepatology at Westmead Hospital (2006-). He has a proven record of delivering high impact research and teaching outcomes as well as demonstrating leadership at both national and international levels. His work spans basic and translational research on pre-cancerous liver diseases (fatty liver disease, viral hepatitis, liver fibrosis and cirrhosis) and liver cancer.

Research interests

Liver Disease and Cancer, Viral Hepatitis, Liver Cancer, Fatty Liver Disease (NAFLD/NASH), Hepatic Drug Metabolism, Host Genetics in Liver Disease, Liver Fibrosis and Injury, Precision Medicine, Genetics and Hepatitis C

Adjunct roles

Robert W Storr Chair of Hepatic Medicine Sydney Medical School
Head, Department of Gastroenterology & Hepatology Westmead Hospital and Sydney West Local Health District

Current grants

MRFF grant Level 3 investigator grant
Cancer Institute NSW grants
Pharma funding
National Health and Medical Research Council (NHMRC)/Ideas Grant 2022 Oncofetal ecosystem in advanced Hepatocellular Carcinoma: Implications for Identifying Immunotherapy response
National Health and Medical Research Council (NHMRC)/Investigator Grant 2021-2024 Delineating the clinical and molecular heterogeneity of fatty liver disease to inform treatment
Australian Centre for HIV and Hepatitis Virology Research (ACH2)/Research Support 2021 Development of a diagnostic assay to measure hepatitis B virus cccDNA

Affiliations

Sydney Medical School, Westmead Hospital, Sydney Medical School, University of Sydney

Professional Associations and Organisations

2022 - Medical Staff Council, Westmead Hospital Chair
2023 NHRMC Liver Cancer Surveillance Guidelines Chair
2023 Cancer Council Australia, Roadmap to Liver Cancer Control Chair
2023 Australian Liver Faculty (GE Society of Australia [GESA]) Chair
Metabolic fatty Liver Disease Consortium (MAIDEN) of the Asian Pacific Association for the Study of the Liver (APASL) Chair
Australian Liver Faculty (GE Society of Australia [GESA]) Board member
AGITG Scientific Advisory Committee, Executive Council, International Association for Study of Liver (IASL) Member
Clinical Research Committee of the American Association for the Study of Liver (AASLD) Member
AASLD Asia Pacific Regional Advisory Council
Australian National Liver Cancer Collaborative Executive

Awards and recognition

2024 - President Elect, Asian Pacific Association for Study of Liver Disease, Joseph Sung Medical, International Digestive Diseases Forum (Hong Kong),
2025-2029 and 2020-2024 - Honorary Laureate Skou Professor Aarhus University
2021- NSW Premier's Awards for Outstanding Cancer Research,
2021- Sally Crossing AM Award for Research, Cancer Council NSW
2020- Okuda-Omata APASL Distinguished Research Prize
2017 - Asian Pacific Association for Study of Liver Disease, election to AAHMS
2017 - Distinguished Research prize, Gastroenterological Society of Australia
2017 - Elected to Fellowship, Australian Academy of Health and Medical Sciences
2016 Honorary Life Membership of Hepatology Society of Philippines
2015 - NHMRC Award to Sydney Health Partners Advanced Health Research of which Storr Liver Centre is an integral part. Recognised for high quality research internationally
2014 - STREP Grant SRP 08-03 awarded by Cancer Council NSW as one of the ten best projects funded by Cancer Council NSW
2013 - Westmead Millennium Science Prize
2013 - Distinguished Professor Award, University of Sydney
2009 to 2023 - Westmead Millennium Institute annual Science Prizes annually for outstanding research